产品货号：
Z14711
中文名称：
DARC/ACKR1抗体
英文名称：
Anti-DARC/ACKR1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-DARC/ACKR1 Antibody |
| 指标别名 | CCBP1;CD234;DARC;Dfy;FY;Fy glycoprotein;Glycoprotein D;GPD;GpFy;Plasmodium vivax receptor;WBCQ1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC |
| 基因名称 | ACKR1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | DARC antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human DARC.The immunogen is located within the last 50 amino acids of DARC. |
| 计算分子量 | 36kDa |
| 成分 | DARC Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | DARC Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | DARC,also known as the Duffy antigen/chemokine receptor,is a seven-transmembrane protein homologous to the classical chemokine G-protein coupled receptors (GPCRs) with the exception of the motif required for G protein coupling.DARC can bind with high affinity several chemokines without transducing any signal,suggesting it may modulate the signals normally induced by these chemokines.Recently,DARC was found to interact with KAI1,a four transmembrane protein recently identified as a tumor metastasis suppressor protein.It is thought that tumor cells dislodged from the primary tumor and expressing KAI1 interact with DARC proteins expressed on vascular cells,transmitting a senescent signal to the tumor cells,while tumor cells that have lost KAI1 expression can proliferate and potentially give rise to metastases.At least three isoforms of DARC are known to exist. |
| Uniprot ID | Q16570 |
| 基因名全称 | Duffy blood group,chemokine receptor |
| 蛋白名全称 | Duffy blood group,chemokine receptor |
| 推荐稀释比 | DARC antibody can be used for detection of DARC by Western blot at 0.5 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.Antibody validated:Western Blot in human samples and Immunohistochemistry in mouse samples.All other applications and species not yet tested. |
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